Topological gene expression networks recapitulate brain anatomy and function

Understanding how gene expression translates to and affects human behavior is one of the ultimate goals of neuroscience. In this paper, we present a pipeline based on Mapper, a topological simplification tool, to analyze gene co-expression data. We first validate the method by reproducing key result...

Full description

Bibliographic Details
Main Authors: Alice Patania, Pierluigi Selvaggi, Mattia Veronese, Ottavia Dipasquale, Paul Expert, Giovanni Petri
Format: Article
Language:English
Published: The MIT Press 2019-07-01
Series:Network Neuroscience
Subjects:
Online Access:https://www.mitpressjournals.org/doi/pdf/10.1162/netn_a_00094