Negative Survival Impact of High Radiation Doses to Neural Stem Cells Niches in an IDH-Wild-Type Glioblastoma Population

Negative Survival Impact of High Radiation Doses to Neural Stem Cells Niches in an IDH-Wild-Type Glioblastoma Population

Aims: Assess the impact of radiation doses to neural stem cell (NSC) niches in patients with IDH-wild-type glioblastoma.Materials and Methods: Fifty patients were included in the study. NSC niches [SubVentricular Zone (SVZ) and Sub Granular Zone (SGZ)] were contoured by fusing CT scans and pre-thera...

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Bibliographic Details
Main Authors: Xavier Muracciole, Wassim El-amine, Emmeline Tabouret, Mohamed Boucekine, Anne Barlier, Gregorio Petrirena, Tovo Harivony, Laetitia Solignac, Olivier L. Chinot, Nicolas Macagno, Dominique Figarella-Branger, Laetitia Padovani
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-10-01
Series:Frontiers in Oncology
Subjects:
glioblastoma
MGMT
stem neural niches
radiotherapy
dose
survival impact
Online Access:https://www.frontiersin.org/article/10.3389/fonc.2018.00426/full

Internet

https://www.frontiersin.org/article/10.3389/fonc.2018.00426/full

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