Myc-associated zinc-finger protein promotes clear cell renal cell carcinoma progression through transcriptional activation of the MAP2K2-dependent ERK pathway

Myc-associated zinc-finger protein promotes clear cell renal cell carcinoma progression through transcriptional activation of the MAP2K2-dependent ERK pathway

Abstract Background The dysfunction of myc-related zinc finger protein (MAZ) has been proven to contribute to tumorigenesis and development of multiple cancer types. However, the biological roles and clinical significance of MAZ in clear cell renal carcinoma (ccRCC) remain unclear. Methods MAZ expre...

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Bibliographic Details
Main Authors: Li-Xin Ren, Jin-Chun Qi, An-Ning Zhao, Bei Shi, Hong Zhang, Dan-Dan Wang, Zhan Yang
Format: Article
Language:English
Published: BMC 2021-06-01
Series:Cancer Cell International
Subjects:
MAZ
MAP2K2
ERK
Signaling pathway
Clear cell renal carcinoma
Online Access:https://doi.org/10.1186/s12935-021-02020-9

Internet

https://doi.org/10.1186/s12935-021-02020-9

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