Triphlorethol-A from Ecklonia cava Up-Regulates the Oxidant Sensitive 8-Oxoguanine DNA Glycosylase 1

Triphlorethol-A from Ecklonia cava Up-Regulates the Oxidant Sensitive 8-Oxoguanine DNA Glycosylase 1

This study investigated the protective mechanisms of triphlorethol-A, isolated from Ecklonia cava, against oxidative stress-induced DNA base damage, especially 8-oxoguanine (8-oxoG), in Chinese hamster lung fibroblast V79-4 cells. 8-Oxoguanine DNA glycosylase-1 (OGG1) plays an important role in the...

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Bibliographic Details
Main Authors: Ki Cheon Kim, In Kyung Lee, Kyoung Ah Kang, Mei Jing Piao, Min Ju Ryu, Jeong Mi Kim, Nam Ho Lee, Jin Won Hyun
Format: Article
Language:English
Published: MDPI AG 2014-10-01
Series:Marine Drugs
Subjects:
antioxidant response elements
8-oxoguanine
Nrf2
OGG1
Triphlorethol-A
Online Access:http://www.mdpi.com/1660-3397/12/11/5357

Internet

http://www.mdpi.com/1660-3397/12/11/5357

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