Oridonin, a Promising ent-Kaurane Diterpenoid Lead Compound

Oridonin, a Promising ent-Kaurane Diterpenoid Lead Compound

Oridonin belongs to ent-kaurane tetracyclic diterpenoid and was first isolated from Isodon species. It exhibits inhibitory activities against a variety of tumor cells, and pharmacological study shows that oridonin could inhibit cell proliferation, DNA, RNA and protein synthesis of cancer cells, indu...

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Bibliographic Details
Main Authors: Dahong Li, Tong Han, Jie Liao, Xu Hu, Shengtao Xu, Kangtao Tian, Xiaoke Gu, Keguang Cheng, Zhanlin Li, Huiming Hua, Jinyi Xu
Format: Article
Language:English
Published: MDPI AG 2016-08-01
Series:International Journal of Molecular Sciences
Subjects:
oridonin
ent-kaurane
medicinal chemistry
structural modification
biological activity
Online Access:http://www.mdpi.com/1422-0067/17/9/1395

Internet

http://www.mdpi.com/1422-0067/17/9/1395

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