Effect of Multiple Vaccinations with Tumor Cell-Based Vaccine with Codon-Modified GM-CSF on Tumor Growth in a Mouse Model

Effect of Multiple Vaccinations with Tumor Cell-Based Vaccine with Codon-Modified GM-CSF on Tumor Growth in a Mouse Model

Ectopic expression of codon-modified granulocyte-macrophage colony-stimulating factor (cGM-CSF) in TC-1 cells (TC-1/cGM-CSF), a model cell line for human papillomavirus (HPV)-infected cervical cancer cells, increased the expression level of GM-CSF and improved the efficacy of tumor cell-based vaccin...

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Bibliographic Details
Main Authors: Jiantai Timothy Qiu, Donia Alson, Ta-Hsien Lee, Ching-Chou Tsai, Ting-We Yu, Yu-Sing Chen, Ya-Fang Cheng, Chu-Chi Lin, Scott C. Schuyler
Format: Article
Language:English
Published: MDPI AG 2019-03-01
Series:Cancers
Subjects:
HPV
cGM-CSF
cervical cancer
multiple vaccinations
IKDCs
Online Access:http://www.mdpi.com/2072-6694/11/3/368

Internet

http://www.mdpi.com/2072-6694/11/3/368

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