Conventional Co-Housing Modulates Murine Gut Microbiota and Hematopoietic Gene Expression

Conventional Co-Housing Modulates Murine Gut Microbiota and Hematopoietic Gene Expression

Specific-pathogen-free (SPF) mice have improved hematopoietic characteristics relative to germ-free mice, however, it is not clear whether improvements in hematopoietic traits will continue when the level of microorganism exposure is further increased. We co-housed SPF C57BL/6 mice in a conventional...

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Bibliographic Details
Main Authors: Jichun Chen, Shuling Zhang, Xingmin Feng, Zhijie Wu, Wendy Dubois, Vishal Thovarai, Sonia Ahluwalia, Shouguo Gao, Jinguo Chen, Tyler Peat, Shurjo K. Sen, Giorgio Trinchieri, Neal S. Young, Beverly A. Mock
Format: Article
Language:English
Published: MDPI AG 2020-08-01
Series:International Journal of Molecular Sciences
Subjects:
mice
specific pathogen free
conventional co-housing
gut microbiota
single cell RNA-seq
hematopoietic stem and progenitor cells
Online Access:https://www.mdpi.com/1422-0067/21/17/6143

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https://www.mdpi.com/1422-0067/21/17/6143

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