Delayed onset of experimental autoimmune encephalomyelitis in Olig1 deficient mice.

BACKGROUND: Olig1 is a basic helix-loop-helix (bHLH) transcription factor that is essential for oligodendrogenesis and efficient remyelination. However, its role in neurodegenerative disorders has not been well-elucidated. METHODOLOGY/PRINCIPAL FINDINGS: Here we investigated the effects of Olig1 def...

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Bibliographic Details
Main Authors: Xiaoli Guo, Chikako Harada, Kazuhiko Namekata, Yoshinori Mitamura, Hiroshi Yoshida, Yoh Matsumoto, Takayuki Harada
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2947525?pdf=render