The Roles of Peyer's Patches and Microfold Cells in the Gut Immune System: Relevance to Autoimmune Diseases

The Roles of Peyer's Patches and Microfold Cells in the Gut Immune System: Relevance to Autoimmune Diseases

Microfold (M) cells are located in the epithelium covering mucosa-associated lymphoid tissues, such as the Peyer's patches (PPs) of the small intestine. M cells actively transport luminal antigens to the underlying lymphoid follicles to initiate an immune response. The molecular machinery of M-...

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Bibliographic Details
Main Authors: Nobuhide Kobayashi, Daisuke Takahashi, Shunsuke Takano, Shunsuke Kimura, Koji Hase
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-10-01
Series:Frontiers in Immunology
Subjects:
mucosal immunity
autoimmune disease
microfold cell
Peyer's patch
intestinal microbiota
intestinal epithelial cell
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2019.02345/full

Internet

https://www.frontiersin.org/article/10.3389/fimmu.2019.02345/full

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