Determination of Heavy Metal Concentrations in Normal and Pathological Human Endometrial Biopsies and In Vitro Regulation of Gene Expression by Metals in the Ishikawa and Hec-1b Endometrial Cell Line.

It is well known that several metals, such as lead, mercury, cadmium, and vanadium, can mimic the effects of estrogens (metallo-estrogens). Nevertheless, there are only a few studies that have assessed the effects of toxic metals on the female genital tract and, in particular, endometrial tissue. In...

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Main Authors: Erwan Guyot, Yevgeniya Solovyova, Céline Tomkiewicz, Alix Leblanc, Stéphane Pierre, Souleiman El Balkhi, Marie-Aude Le Frère-Belda, Fabrice Lecuru, Joël Poupon, Robert Barouki, Martine Aggerbeck, Xavier Coumoul
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4657954?pdf=render