Protective efficacy of folic acid and vitamin B12 against nicotine-induced toxicity in pancreatic islets of the rat
Although cigarette smoking is associated with insulin resistance and an increased risk for type 2 diabetes, few studies have examined the effect of nicotine on the adult endocrine pancreas. In this study, male Wister rats were treated with nicotine (3 mg/kg body weight/day) with or without supplemen...
Main Authors: | , , , , , , |
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Format: | Article |
Language: | English |
Published: |
Sciendo
2015-06-01
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Series: | Interdisciplinary Toxicology |
Subjects: | |
Online Access: | https://doi.org/10.1515/intox-2015-0016 |