Submitted for your consideration: potential advantages of a novel clinical trial design and initial patient reaction

In many circumstances, individuals do not respond identically to the same treatment. This phenomenon, which is called treatment response heterogeneity (TRH), appears to be present in treatments for many conditions, including obesity. Estimating the total amount of TRH, predicting an individual’s res...

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Bibliographic Details
Main Authors: Matthew Shane Loop, Alexis C. Frazier-Wood, Amy S. Thomas, Emily J. Dhurandhar, James M. Shikany, Gary L. Gadbury, David B Allison
Format: Article
Language:English
Published: Frontiers Media S.A. 2012-08-01
Series:Frontiers in Genetics
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fgene.2012.00145/full