The monoaminergic pathways and inhibition of monoamine transporters interfere with the antidepressive-like behavior of ketamine

Ketamine (KET), a NMDA receptor antagonist, has been studied for its rapid and efficacious antidepressant effect, even for the treatment-resistant depression. Although depression is a major cause of disability worldwide, the treatment can be feasible, affordable and cost-effective, decreasing the po...

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Bibliographic Details
Main Authors: Glauce Socorro de Barros Viana, Cecilia Coelho Xavier, Eduardo Mulato do Vale, Maria Janice Pereira Lopes, Viviane de Jesus Alves, Roberta de Oliveira Costa, Kelly Rose Tavares Neves
Format: Article
Language:English
Published: Elsevier 2018-06-01
Series:IBRO Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2451830117300328