Chronic Stress Weakens Connectivity in the Prefrontal Cortex: Architectural and Molecular Changes
Chronic exposure to uncontrollable stress causes loss of spines and dendrites in the prefrontal cortex (PFC), a recently evolved brain region that provides top-down regulation of thought, action, and emotion. PFC neurons generate top-down goals through recurrent excitatory connections on spines. Thi...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
| Published: |
SAGE Publishing
2021-08-01
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| Series: | Chronic Stress |
| Online Access: | https://doi.org/10.1177/24705470211029254 |