Development of a Patient-Derived Xenograft (PDX) of Breast Cancer Bone Metastasis in a Zebrafish Model

Development of a Patient-Derived Xenograft (PDX) of Breast Cancer Bone Metastasis in a Zebrafish Model

Bone metastasis is a complex process that needs to be better understood in order to help clinicians prevent and treat it. Xenografts using patient-derived material (PDX) rather than cancer cell lines are a novel approach that guarantees more clinically realistic results. A primary culture of bone me...

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Bibliographic Details
Main Authors: Laura Mercatali, Federico La Manna, Arwin Groenewoud, Roberto Casadei, Federica Recine, Giacomo Miserocchi, Federica Pieri, Chiara Liverani, Alberto Bongiovanni, Chiara Spadazzi, Alessandro de Vita, Gabri van der Pluijm, Andrea Giorgini, Roberto Biagini, Dino Amadori, Toni Ibrahim, Ewa Snaar-Jagalska
Format: Article
Language:English
Published: MDPI AG 2016-08-01
Series:International Journal of Molecular Sciences
Subjects:
bone metastasis
zebrafish model
breast cancer
patient-derived xenograft
Online Access:http://www.mdpi.com/1422-0067/17/8/1375

Internet

http://www.mdpi.com/1422-0067/17/8/1375

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