Icariin Is A PPARα Activator Inducing Lipid Metabolic Gene Expression in Mice

Icariin is effective in the treatment of hyperlipidemia. To understand the effect of icariin on lipid metabolism, effects of icariin on PPARα and its target genes were investigated. Mice were treated orally with icariin at doses of 0, 100, 200, and 400 mg/kg, or clofibrate (500 mg/kg) for five days....

Full description

Bibliographic Details
Main Authors: Yuan-Fu Lu, Yun-Yan Xu, Feng Jin, Qin Wu, Jing-Shan Shi, Jie Liu
Format: Article
Language:English
Published: MDPI AG 2014-11-01
Series:Molecules
Subjects:
Online Access:http://www.mdpi.com/1420-3049/19/11/18179