Screening for Combination Cancer Therapies With Dynamic Fuzzy Modeling and Multi-Objective Optimization

Combination therapies proved to be a valuable strategy in the fight against cancer, thanks to their increased efficacy in inducing tumor cell death and in reducing tumor growth, metastatic potential, and the risk of developing drug resistance. The identification of effective combinations of drug tar...

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Bibliographic Details
Main Authors: Simone Spolaor, Martijn Scheve, Murat Firat, Paolo Cazzaniga, Daniela Besozzi, Marco S. Nobile
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-03-01
Series:Frontiers in Genetics
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fgene.2021.617935/full