Amelioration of Endothelial Dysfunction in Diabetes: Role of Takeda G Protein–Coupled Receptor 5

Amelioration of Endothelial Dysfunction in Diabetes: Role of Takeda G Protein–Coupled Receptor 5

Diabetes mellitus (DM) eventually leads to chronic vascular complications, resulting in cardiovascular diseases. DM-associated endothelial dysfunction (ED) plays an important role in the development of chronic vascular complications. Low endothelial nitric oxide synthase (eNOS) activity, inflammatio...

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Bibliographic Details
Main Authors: Zhengyao Cai, Suxin Yuan, Yi Zhong, Li Deng, Jiafu Li, Xiaoqiu Tan, Jian Feng
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-04-01
Series:Frontiers in Pharmacology
Subjects:
diabetes mellitus
endothelial dysfunction
TGR5
endothelial nitric oxide synthase
inflammation
oxidative stress
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2021.637051/full

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https://www.frontiersin.org/articles/10.3389/fphar.2021.637051/full

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