Histidine-rich glycoprotein can prevent development of mouse experimental glioblastoma.

Extensive angiogenesis, formation of new capillaries from pre-existing blood vessels, is an important feature of malignant glioma. Several antiangiogenic drugs targeting vascular endothelial growth factor (VEGF) or its receptors are currently in clinical trials as therapy for high-grade glioma and b...

Full description

Bibliographic Details
Main Authors: Maria Kärrlander, Nanna Lindberg, Tommie Olofsson, Marianne Kastemar, Anna-Karin Olsson, Lene Uhrbom
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2795204?pdf=render