Efficacy of Posaconazole Prophylaxis for Fungal Disease in Hematology Patients Treated With Chemotherapy and Transplantation: An Open-Label, Prospective, Observational Study

Efficacy of Posaconazole Prophylaxis for Fungal Disease in Hematology Patients Treated With Chemotherapy and Transplantation: An Open-Label, Prospective, Observational Study

BackgroundPosaconazole (PCZ) is used prophylactically to prevent invasive fungal infections (IFIs) in patients with hematological malignancies.ObjectiveTo evaluate the cut-off serum concentration of PCZ for successful IFI prophylaxis in Chinese subjects.Patients and MethodsA total of 74 patients tre...

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Bibliographic Details
Main Authors: Weiyang Li, Fan Xia, Haixia Zhou, Huiying Qiu, Depei Wu, Xiao Ma, Aining Sun
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-03-01
Series:Frontiers in Microbiology
Subjects:
invasive fungal infection
posaconazole
serum drug concentration
antifungal prophylaxis
Chinese hematology patients
Online Access:https://www.frontiersin.org/article/10.3389/fmicb.2020.00349/full

Internet

https://www.frontiersin.org/article/10.3389/fmicb.2020.00349/full

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