GRHL3 binding and enhancers rearrange as epidermal keratinocytes transition between functional states.
Transcription factor binding, chromatin modifications and large scale chromatin re-organization underlie progressive, irreversible cell lineage commitments and differentiation. We know little, however, about chromatin changes as cells enter transient, reversible states such as migration. Here we dem...
Main Authors: | , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2017-04-01
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Series: | PLoS Genetics |
Online Access: | https://doi.org/10.1371/journal.pgen.1006745 |