Progress and Challenges in Developing Aptamer-Functionalized Targeted Drug Delivery Systems

Progress and Challenges in Developing Aptamer-Functionalized Targeted Drug Delivery Systems

Aptamers, which can be screened via systematic evolution of ligands by exponential enrichment (SELEX), are superior ligands for molecular recognition due to their high selectivity and affinity. The interest in the use of aptamers as ligands for targeted drug delivery has been increasing due to their...

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Bibliographic Details
Main Authors: Feng Jiang, Biao Liu, Jun Lu, Fangfei Li, Defang Li, Chao Liang, Lei Dang, Jin Liu, Bing He, Shaikh Atik Badshah, Cheng Lu, Xiaojuan He, Baosheng Guo, Xiao-Bing Zhang, Weihong Tan, Aiping Lu, Ge Zhang
Format: Article
Language:English
Published: MDPI AG 2015-10-01
Series:International Journal of Molecular Sciences
Subjects:
aptamer-functionalized targeted drug delivery systems
aptamer
SELEX
aptamer-small molecule conjugated systems
aptamer-nanomaterial conjugated systems
Online Access:http://www.mdpi.com/1422-0067/16/10/23784

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http://www.mdpi.com/1422-0067/16/10/23784

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