The frequency of CCR5 promoter polymorphisms and CCR5 32 mutation in Iranian populations

Evidence showed that chemokines serve as pro-migratory factors for immune cells. CCL3, CCL4 and CCL5, as the main CC  chemokines subfamily members, activate immune cells through binding to CC chemokine receptor 5 or CCR5. Macrophages, NK cells and T lymphocytes express CCR5 and thus, affected CCR5 e...

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Bibliographic Details
Main Authors: Mohammad Zare-Bidaki, Masoud Karimi-Googheri, Gholamhossein Hassanshahi, Nahid Zainodini, Mohammad Kazemi Arababadi
Format: Article
Language:English
Published: Mashhad University of Medical Sciences 2015-04-01
Series:Iranian Journal of Basic Medical Sciences
Subjects:
Online Access:http://ijbms.mums.ac.ir/pdf_4278_29d40ed5f135e3a7d405db47b6caf413.html