Gilteritinib: a novel FLT3 inhibitor for acute myeloid leukemia

Gilteritinib: a novel FLT3 inhibitor for acute myeloid leukemia

Abstract FMS-like tyrosine kinase 3- internal tandem duplication (FLT3-ITD) remains as one of the most frequently mutated genes in acute myeloid leukemia (AML), especially in those with normal cytogenetics. The FLT3-ITD and FLT3-TKD (tyrosine kinase domain) mutations are biomarkers for high risk AML...

Full description

Bibliographic Details
Main Authors: Juanjuan Zhao, Yongping Song, Delong Liu
Format: Article
Language:English
Published: BMC 2019-09-01
Series:Biomarker Research
Subjects:
FLT3
Gilteritinib
Tyrosine kinase inhibitor
FLT3 inhibitor
Online Access:http://link.springer.com/article/10.1186/s40364-019-0170-2

Internet

http://link.springer.com/article/10.1186/s40364-019-0170-2

Similar Items