IGF-1, IGFBP-1, and IGFBP-3 polymorphisms predict circulating IGF levels but not breast cancer risk: findings from the Breast and Prostate Cancer Cohort Consortium (BPC3).

IGF-1, IGFBP-1, and IGFBP-3 polymorphisms predict circulating IGF levels but not breast cancer risk: findings from the Breast and Prostate Cancer Cohort Consortium (BPC3).

IGF-1 has been shown to promote proliferation of normal epithelial breast cells, and the IGF pathway has also been linked to mammary carcinogenesis in animal models. We comprehensively examined the association between common genetic variation in the IGF1, IGFBP1, and IGFBP3 genes in relation to circ...

Full description

Bibliographic Details
Main Authors: Alpa V Patel, Iona Cheng, Federico Canzian, Loïc Le Marchand, Michael J Thun, Christine D Berg, Julie Buring, Eugenia E Calle, Stephen Chanock, Francoise Clavel-Chapelon, David G Cox, Miren Dorronsoro, Laure Dossus, Christopher A Haiman, Susan E Hankinson, Brian E Henderson, Robert Hoover, David J Hunter, Rudolf Kaaks, Laurence N Kolonel, Peter Kraft, Jakob Linseisen, Eiliv Lund, Jonas Manjer, Catherine McCarty, Petra H M Peeters, Malcolm C Pike, Michael Pollak, Elio Riboli, Daniel O Stram, Anne Tjonneland, Ruth C Travis, Dimitrios Trichopoulos, Rosario Tumino, Meredith Yeager, Regina G Ziegler, Heather Spencer Feigelson, Breast and Prostate Cancer Cohort Consortium
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2008-07-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2440354?pdf=render

Internet

http://europepmc.org/articles/PMC2440354?pdf=render

Similar Items