Effects of hyperoxia on vascular tone in animal models: systematic review and meta-analysis

Abstract Background Arterial hyperoxia may induce vasoconstriction and reduce cardiac output, which is particularly undesirable in patients who already have compromised perfusion of vital organs. Due to the inaccessibility of vital organs in humans, vasoconstrictive effects of hyperoxia have primari...

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Main Authors: Bob Smit, Yvo M. Smulders, Etto C. Eringa, Heleen M. Oudemans - van Straaten, Armand R. J. Girbes, Kimberley E. Wever, Carlijn R. Hooijmans, Angelique M. E. Spoelstra - de Man
Format: Article
Language:English
Published: BMC 2018-08-01
Series:Critical Care
Subjects:
Online Access:http://link.springer.com/article/10.1186/s13054-018-2123-9