Biological Evaluation and Docking Analysis of Potent BACE1 Inhibitors from Boesenbergia rotunda

Alzheimer’s disease (AD) is an irreversible neurodegenerative disorder characterized by progressive impairment of cognitive functions. Beta-site amyloid precursor protein cleaving enzyme1 (BACE1) is essential for the formation of β-amyloid peptide (Aβ), a major constituen...

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Bibliographic Details
Main Authors: Kumju Youn, Mira Jun
Format: Article
Language:English
Published: MDPI AG 2019-03-01
Series:Nutrients
Subjects:
Online Access:http://www.mdpi.com/2072-6643/11/3/662