Tetrodotoxin (TTX) as a Therapeutic Agent for Pain

Tetrodotoxin (TTX) as a Therapeutic Agent for Pain

Tetrodotoxin (TTX) is a potent neurotoxin that blocks voltage-gated sodium channels (VGSCs). VGSCs play a critical role in neuronal function under both physiological and pathological conditions. TTX has been extensively used to functionally characterize VGSCs, which can be classified as TTX-sensitiv...

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Bibliographic Details
Main Authors: Cruz Miguel Cendán, Cristina Sánchez-Fernández, Rafael González-Cano, Miguel Ángel Tejada, Enrique José Cobos, Francisco Rafael Nieto
Format: Article
Language:English
Published: MDPI AG 2012-01-01
Series:Marine Drugs
Subjects:
tetrodotoxin
TTX
TTX-sensitive voltage-gated sodium channels
pain
neuropathic pain
Online Access:http://www.mdpi.com/1660-3397/10/2/281/

Internet

http://www.mdpi.com/1660-3397/10/2/281/

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