Anti-prion activity of Brilliant Blue G.

BACKGROUND: Prion diseases are fatal neurodegenerative disorders with no effective therapy currently available. Accumulating evidence has implicated over-activation of P2X7 ionotropic purinergic receptor (P2X7R) in the progression of neuronal loss in several neurodegenerative diseases. This has led...

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Bibliographic Details
Main Authors: Yoshifumi Iwamaru, Takato Takenouchi, Yuichi Murayama, Hiroyuki Okada, Morikazu Imamura, Yoshihisa Shimizu, Makoto Hashimoto, Shirou Mohri, Takashi Yokoyama, Hiroshi Kitani
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3365075?pdf=render