A Systems’ Biology Approach to Study MicroRNA-Mediated Gene Regulatory Networks

MicroRNAs (miRNAs) are potent effectors in gene regulatory networks where aberrant miRNA expression can contribute to human diseases such as cancer. For a better understanding of the regulatory role of miRNAs in coordinating gene expression, we here present a systems biology approach combining data-...

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Bibliographic Details
Main Authors: Xin Lai, Animesh Bhattacharya, Ulf Schmitz, Manfred Kunz, Julio Vera, Olaf Wolkenhauer
Format: Article
Language:English
Published: Hindawi Limited 2013-01-01
Series:BioMed Research International
Online Access:http://dx.doi.org/10.1155/2013/703849