Maternal Antiviral Immunoglobulin Accumulates in Neural Tissue of Neonates To Prevent HSV Neurological Disease

While antibody responses to neurovirulent pathogens are critical for clearance, the extent to which antibodies access the nervous system to ameliorate infection is poorly understood. In this study on herpes simplex virus 1 (HSV-1), we demonstrate that HSV-specific antibodies are present during HSV-1...

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Bibliographic Details
Main Authors: Yike Jiang, Chaya D. Patel, Richard Manivanh, Brian North, Iara M. Backes, David A. Posner, Francesca Gilli, Andrew R. Pachner, Lananh N. Nguyen, David A. Leib, Anne Moscona
Format: Article
Language:English
Published: American Society for Microbiology 2017-07-01
Series:mBio
Online Access:http://mbio.asm.org/cgi/content/full/8/4/e00678-17