Biochemical Characterization of Glutamate Racemase-A New Candidate Drug Target against Burkholderia cenocepacia Infections.

The greatest obstacle for the treatment of cystic fibrosis patients infected with the Burkholderia species is their intrinsic antibiotic resistance. For this reason, there is a need to develop new effective compounds. Glutamate racemase, an essential enzyme for the biosynthesis of the bacterial cell...

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Bibliographic Details
Main Authors: Aygun Israyilova, Silvia Buroni, Federico Forneris, Viola Camilla Scoffone, Namiq Q Shixaliyev, Giovanna Riccardi, Laurent Roberto Chiarelli
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5127577?pdf=render