Human Pancreatic Islet Preparations Release HMGB1: (Ir)Relevance for Graft Engraftment
High levels of donor-derived high-mobility group box 1 (HMGB1) protein have been associated with poor islet graft outcome in mouse models. The aim of our work was to determine whether HMGB1 released by human islets had independent proinflammatory effects that influence engraftment in humans. Human i...
| Main Authors: | , , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
SAGE Publishing
2013-11-01
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| Series: | Cell Transplantation |
| Online Access: | https://doi.org/10.3727/096368912X657783 |