HY immune tolerance is common in women without male offspring.

Sex difference is an established risk factor for hematopoietic stem cell transplantation (HSCT)-related complications like graft versus host disease (GVHD). CD8pos cytotoxic T cells specific for Y chromosome-encoded minor Histocompatibility antigens (HY) play an important role therein. Prior to HSC...

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Bibliographic Details
Main Authors: Miranda P Dierselhuis, Ewa Jankowska-Gan, Els Blokland, Jos Pool, William J Burlingham, Astrid G S van Halteren, Els Goulmy
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3960116?pdf=render