Gene expression within the periaqueductal gray is linked to vocal behavior and early-onset parkinsonism in Pink1 knockout rats

Gene expression within the periaqueductal gray is linked to vocal behavior and early-onset parkinsonism in Pink1 knockout rats

Abstract Background Parkinson’s disease (PD) is a degenerative disease with early-stage pathology hypothesized to manifest in brainstem regions. Vocal deficits, including soft, monotone speech, result in significant clinical and quality of life issues and are present in 90% of PD patients; yet the u...

Full description

Bibliographic Details
Main Authors: Cynthia A. Kelm-Nelson, Stephen Gammie
Format: Article
Language:English
Published: BMC 2020-09-01
Series:BMC Genomics
Subjects:
Parkinson’s disease
Rat
Pink1
RNA sequencing
WGCNA
Bioinformatics
Online Access:http://link.springer.com/article/10.1186/s12864-020-07037-4

Internet

http://link.springer.com/article/10.1186/s12864-020-07037-4

Similar Items