The comparison of predictive performance in bispectral index prediction during target effect-site controlled infusion of propofol using different blood effect-site equilibration rate constants in the same pharmacokinetic model

The comparison of predictive performance in bispectral index prediction during target effect-site controlled infusion of propofol using different blood effect-site equilibration rate constants in the same pharmacokinetic model

BackgroundBlood-brain equilibration rate constant (ke0) is derived from either pharmacokinetic and pharmacodynamic modeling (ke0_model) or a model-independent observed time to peak effect (ke0_tpeak). Performance in bispectral index (BIS) prediction was compared between ke0_model and ke0_tpeak for m...

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Bibliographic Details
Main Authors: Byung-Moon Choi, Ji-Youn Bang, Kyeo-Woon Jung, Ju-Hyun Lee, Heon-Yong Bae, Gyu-Jeong Noh
Format: Article
Language:English
Published: Korean Society of Anesthesiologists 2013-10-01
Series:Korean Journal of Anesthesiology
Subjects:
bispectral index
pharmacokinetic
propofol
Online Access:http://ekja.org/upload/pdf/kjae-65-299.pdf

Internet

http://ekja.org/upload/pdf/kjae-65-299.pdf

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