The Y-Box Binding Protein 1 Suppresses Alzheimer's Disease Progression in Two Animal Models.

The Y-box binding protein 1 (YB-1) is a member of the family of DNA- and RNA binding proteins. It is involved in a wide variety of DNA/RNA-dependent events including cell proliferation and differentiation, stress response, and malignant cell transformation. Previously, YB-1 was detected in neurons o...

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Main Authors: N V Bobkova, D N Lyabin, N I Medvinskaya, A N Samokhin, P V Nekrasov, I V Nesterova, I Y Aleksandrova, O G Tatarnikova, A G Bobylev, I M Vikhlyantsev, M S Kukharsky, A A Ustyugov, D N Polyakov, I A Eliseeva, D A Kretov, S G Guryanov, L P Ovchinnikov
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4578864?pdf=render