Iron Metabolism in the Tumor Microenvironment—Implications for Anti-Cancer Immune Response

Iron Metabolism in the Tumor Microenvironment—Implications for Anti-Cancer Immune Response

New insights into the field of iron metabolism within the tumor microenvironment have been uncovered in recent years. Iron promotes the production of reactive oxygen species, which may either trigger ferroptosis cell death or contribute to malignant transformation. Once transformed, cancer cells div...

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Bibliographic Details
Main Authors: Alessandro Sacco, Anna Martina Battaglia, Cirino Botta, Ilenia Aversa, Serafina Mancuso, Francesco Costanzo, Flavia Biamonte
Format: Article
Language:English
Published: MDPI AG 2021-02-01
Series:Cells
Subjects:
iron metabolism
ferroptosis
cancer
innate immune response
adaptive immune response tumor microenvironment
Online Access:https://www.mdpi.com/2073-4409/10/2/303

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https://www.mdpi.com/2073-4409/10/2/303

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