Mitochondrial Sirtuins in Reproduction

Mitochondria act as hubs of numerous metabolic pathways. Mitochondrial dysfunctions contribute to altering the redox balance and predispose to aging and metabolic alterations. The sirtuin family is composed of seven members and three of them, SIRT3-5, are housed in mitochondria. They catalyze NAD+-d...

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Bibliographic Details
Main Authors: Giovanna Di Emidio, Stefano Falone, Paolo Giovanni Artini, Fernanda Amicarelli, Anna Maria D’Alessandro, Carla Tatone
Format: Article
Language:English
Published: MDPI AG 2021-06-01
Series:Antioxidants
Subjects:
Online Access:https://www.mdpi.com/2076-3921/10/7/1047