Serum neurofilament light levels correlate with severity measures and neurodegeneration markers in autosomal dominant Alzheimer’s disease

Serum neurofilament light levels correlate with severity measures and neurodegeneration markers in autosomal dominant Alzheimer’s disease

Abstract Background Biomarkers that can track disease onset and progression in autosomal dominant Alzheimer’s disease (ADAD) are needed. We investigate whether serum neurofilament light (NfL) concentration is associated with clinical and cerebrospinal fluid (CSF) markers in ADAD. We also evaluate se...

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Bibliographic Details
Main Authors: Raquel Sánchez-Valle, Amanda Heslegrave, Martha S. Foiani, Beatriz Bosch, Anna Antonell, Mircea Balasa, Albert Lladó, Henrik Zetterberg, Nick C. Fox
Format: Article
Language:English
Published: BMC 2018-11-01
Series:Alzheimer’s Research & Therapy
Subjects:
Alzheimer’s disease
Biomarkers
Familial Alzheimer’s disease
Presenilin 1
Neurofilament light
Online Access:http://link.springer.com/article/10.1186/s13195-018-0439-y

Internet

http://link.springer.com/article/10.1186/s13195-018-0439-y

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