Current Status of Latency Reversing Agents Facing the Heterogeneity of HIV-1 Cellular and Tissue Reservoirs

Current Status of Latency Reversing Agents Facing the Heterogeneity of HIV-1 Cellular and Tissue Reservoirs

One of the most explored therapeutic approaches aimed at eradicating HIV-1 reservoirs is the “shock and kill” strategy which is based on HIV-1 reactivation in latently-infected cells (“shock” phase) while maintaining antiretroviral therapy (ART) in order to prevent spreading of the infection by the...

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Bibliographic Details
Main Authors: Amina Ait-Ammar, Anna Kula, Gilles Darcis, Roxane Verdikt, Stephane De Wit, Virginie Gautier, Patrick W. G. Mallon, Alessandro Marcello, Olivier Rohr, Carine Van Lint
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-01-01
Series:Frontiers in Microbiology
Subjects:
HIV-1
latency reversing agents
cure
latency
reservoirs
heterogeneity
Online Access:https://www.frontiersin.org/article/10.3389/fmicb.2019.03060/full

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https://www.frontiersin.org/article/10.3389/fmicb.2019.03060/full

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