Relaxin peptides reduce cellular damage in cultured brain slices exposed to transient oxygen–glucose deprivation: an effect mediated by nitric oxide

The effect of treatment with human relaxins on cell death was studied in oxygen- and glucose-deprived brain slices. In addition, involvement of nitric oxide and the relaxin receptor, RXFP3, was studied. Brain slices (n = 12–18/group) were cultured under standard conditions for two weeks and then exp...

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Bibliographic Details
Main Authors: Nicholas P. DeAdder, Hannah J. Gillam, Brian C. Wilson
Format: Article
Language:English
Published: Canadian Science Publishing 2021-02-01
Series:FACETS
Subjects:
Online Access:https://www.facetsjournal.com/doi/full/10.1139/facets-2020-0029