Isolation of a Genomic Region Affecting Most Components of Metabolic Syndrome in a Chromosome-16 Congenic Rat Model.

Metabolic syndrome is a highly prevalent human disease with substantial genomic and environmental components. Previous studies indicate the presence of significant genetic determinants of several features of metabolic syndrome on rat chromosome 16 (RNO16) and the syntenic regions of human genome. We...

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Main Authors: Lucie Šedová, Michal Pravenec, Drahomíra Křenová, Ludmila Kazdová, Václav Zídek, Michaela Krupková, František Liška, Vladimír Křen, Ondřej Šeda
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4816345?pdf=render