Netrin-1 promotes glioma growth by activating NF-κB via UNC5A

Abstract Gliomas, a common type of brain tumor, are characterized by aggressive infiltration, making it difficultly to cure by surgery. Netrin-1, an extracellular guidance cue critical for neuronal axon path-finding, has been reported to play an important role in cell invasion and migration in sever...

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Bibliographic Details
Main Authors: Jing-Ying Chen, Xiao-Xiao He, Chi Ma, Xin-Min Wu, Xi-Lin Wan, Zhen-Kai Xing, Qing-Qing Pei, Xian-Ping Dong, Dong-Xu Liu, Wen-Cheng Xiong, Xiao-Juan Zhu
Format: Article
Language:English
Published: Nature Publishing Group 2017-07-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-017-05707-0