Interaction of Protease-Activated Receptor 2 with G Proteins and Beta-Arrestin 1 Studied by Bioluminescence Resonance Energy Transfer

G protein-coupled receptors (GPCRs) are well recognized as being able to activate several signaling pathways through the activation of different G proteins as well as other signaling proteins such as beta-arrestins. Therefore, understanding how such multiple GPCR-mediated signaling can be integrated...

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Bibliographic Details
Main Authors: Mohammed Akli eAyoub, Jean-Philippe R Pin
Format: Article
Language:English
Published: Frontiers Media S.A. 2013-12-01
Series:Frontiers in Endocrinology
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fendo.2013.00196/full