The depressor response to intracerebroventricular hypotonic saline is sensitive to TRPV4 antagonist RN1734

Several reports have shown that the periventricular region of the brain, including the paraventricular nucleus (PVN), is critical to sensing and responding to changes in plasma osmolality. Further studies also implicate the transient receptor potential ion channel, type V4 (TRPV4) channel in this h...

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Bibliographic Details
Main Authors: Claire H Feetham, Nic eNunn, Richard eBarrett-Jolley
Format: Article
Language:English
Published: Frontiers Media S.A. 2015-04-01
Series:Frontiers in Pharmacology
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fphar.2015.00083/full