Characterization of Toxoplasma DegP, a rhoptry serine protease crucial for lethal infection in mice.

During the infection process, Apicomplexa discharge their secretory organelles called micronemes, rhoptries and dense granules to sustain host cell invasion, intracellular replication and to modulate host cell pathways and immune responses. Herein, we describe the Toxoplasma gondii Deg-like serine p...

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Bibliographic Details
Main Authors: Gaelle Lentini, Hiba El Hajj, Julien Papoin, Gamou Fall, Alexander W Pfaff, Nadim Tawil, Catherine Braun-Breton, Maryse Lebrun
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2017-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5731766?pdf=render