PCR-based detection of a rare linear DNA in cell culture
<p>The described method allows for detection of rare linear DNA fragments generated during genomic deletions. The predicted limit of the detection is one DNA molecule per 10<sup>7</sup> or more cells. The method is based on anchor PCR and involves gel separation of the linear DNA f...
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| Format: | Article |
| Language: | English |
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BMC
2002-01-01
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| Series: | Biological Procedures Online |
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| Online Access: | http://www.biologicalprocedures.com/bpo/arts/1/36/m36.htm |