Evidence for a role of srGAP3 in the positioning of commissural axons within the ventrolateral funiculus of the mouse spinal cord.

Slit-Robo signaling guides commissural axons away from the floor-plate of the spinal cord and into the longitudinal axis after crossing the midline. In this study we have evaluated the role of the Slit-Robo GTPase activating protein 3 (srGAP3) in commissural axon guidance using a knockout (KO) mouse...

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Bibliographic Details
Main Authors: Claire Bacon, Volker Endris, Irwin Andermatt, Vera Niederkofler, Robert Waltereit, Dusan Bartsch, Esther T Stoeckli, Gudrun Rappold
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3104994?pdf=render