Hepatitis B Vaccine Non-Responders Show Higher Frequencies of CD24highCD38high Regulatory B Cells and Lower Levels of IL-10 Expression Compared to Responders

Hepatitis B Vaccine Non-Responders Show Higher Frequencies of CD24highCD38high Regulatory B Cells and Lower Levels of IL-10 Expression Compared to Responders

BackgroundThe cellular mechanisms involved in the lack of protective antibody response after hepatitis B vaccination are still rather unclear. Regulatory B cells (Breg) known as modulators of B-and T-cell responses may contribute to poor vaccine responsiveness. The current study aimed to investigate...

Full description

Bibliographic Details
Main Authors: Nina Körber, Laureen Pohl, Birgit Weinberger, Beatrix Grubeck-Loebenstein, Andrea Wawer, Percy A. Knolle, Hedwig Roggendorf, Ulrike Protzer, Tanja Bauer
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-09-01
Series:Frontiers in Immunology
Subjects:
regulatory B cells
IL-10 expression
vaccine non-responsiveness
hepatitis B vaccination
B10+ cells
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2021.713351/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2021.713351/full

Similar Items